Register for Gordon conference on Nox family NADPH oxidases in June
The 2016 Gordon Research Conference on Nox Family NADPH Oxidases will be held June 5 through June 10 in Waterville Valley, N.H.
Nox family NADPH oxidases are the main dedicated enzyme sources of reactive oxygen species in most cells. Initially described as effectors of microbial killing in phagocytes, research about Noxes virtually exploded upon the identification of several homologues in virtually every cell type in metazoans, and further research is identifying Nox-simile enzymes in more ancestral organisms. Such Nox-related subcelular redox signaling depends on the subtype of catalytic complex expressed in a given cell, as well as the nature of regulatory subunits and associated proteins. Nox-dependent signaling is involved in the regulation of fundamental physiologic events such as cellular survival, proliferation, migration, apoptosis, metabolic adaptations and responses to stress. These events influence host defenses, response to exercise, vascular remodeling, inflammation, mechanoadaptation, tumorigenesis, neurodegeneration and several other disease-associated processes. Consequently, Noxes have emerged as viable and highly promising therapeutic targets.
The Gordon conference program is organized around the theme “NOX molecular insights leading to translation.”
Session topics include:
- the molecular structure of NOX complexes,
- genetic/epigenetic regulation,
- NOX-mediated inflammation and metabolic regulation,
- novel modes of NOX regulation and
- translational studies on gastrointestinal, cardiovascular, neurologic diseases and cancer, including discussions on novel NOX inhibitors.
In addition, a keynote session will feature broad and thought-provoking discussions on redox processes.
The conference will provide a venue for innovative and paradigm-challenging presentations, given by internationally recognized experts and followed by ample time for discussions chaired by discussion leaders. This healthy interaction will be sustained and extended at poster sessions, focused on early-career investigators.
The meeting was organized to reflect gender and geographic diversity of the field and will allow for the inclusion of late-breaking science and speakers selected from trainee abstracts.
The accompanying “NOX Family NADPH Oxidases” Gordon Research Seminar will feature discussions on NOX-related science directed at young investigators and mentoring aspects of career development led by senior scientists, together with oral and poster presentations.
The research conference will further consolidate the NOX scientific community to support our investigation on this vigorously evolving area.
Please join us on this exciting meeting!
For more information, please visit the conference homepage.
Chair, 2016 Gordon Research Conference on Nox Family
NADPH Oxidases, June 5-10, Waterville Valley, N.H.