First international workshop on acetyltransferases, sulfotransferases and UDP-glucuronosyltransferases

Guest post by David W. Hein, University of Louisville for the internal and external advisory committees | The first integrated international workshop on acetyltransferases, sulfotransferases, and UDP-glucuronosyltransferases, scheduled for April 1–3, 2020, in Louisville, Kentucky, builds upon the success of past international workshops that focused on a single xenobiotic metabolizing enzyme system. 

A key purpose and knowledge gap to be met by the integrated workshop is understanding the role of the xenobiotic metabolizing enzymes in environmental health as a group rather than individually. 

This integration theme was a key rationale for selection of many of the keynote speakers.

In an era where powerful genomic technologies are accelerating research into the complex gene–environment interactions modulating the biological effects of xenobiotics (drugs, carcinogens etc.), it is critical to include other major families of phase II conjugation enzymes within the context of an integrated workshop. 

The workshop will open new channels of interaction and collaboration across a broader scientific community, invigorating the field and expanding its global impact. It will provide important consensus information on the proper use of gene and allelic symbols, as well as for conveying recommendations by the HUGO Gene Nomenclature Committee, the PharmacoGenomics KnowledgeBase, the Human Genome Variation Society, etc.

The workshop will promote constructive discussion toward harmonization of pharmacogenetic nomenclature and test result reporting for phase II conjugation enzymes, a need recently recognized by an international workgroup of experts led by scientists of the US Centers of Disease Control and Prevention (Clin. Pharmacol. Ther. 2016, 99:172‐85). 

Abstracts submitted by Nov. 1 will be considered for platform presentations.  Further information available at http://louisville.edu/envirome/fii-workshop-2020.

Photo by Scott Oves.

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